Long Story Short Episode 58: MTHFR Gene Mutation and the Risk of Clotting

In the United States, 20-40% of whites and hispanics have MTHFR gene mutation (C677T). This mutation leads to reduced function of MTHFR enzyme to 65% of normal. The second most common mutation leads to reduced function of MTHFR enzyme, to 30% of normal. The result of these performance issues is reduced methyl groups' availability for methylation functions. The likelihood of …