Lecture abstract: My presentation will focus on the three primary mechanisms of damage identified as the cause of the cascade of progressive and debilitating symptoms in our long COVID patients, whether from contracting the virus and/or from the vaccines. I will then review three of the five modalities we have been using that have proven remarkably effective. These include IV ozone therapy, EBOO/F, and IV therapies listed above (such as PDT), the majority of which effectively target mitochondrial health. These, together with stem cells and hyperbaric oxygen, have resulted in a speedy and complete recovery for approximately 70% of our patients. The rest, though not yet optimally recovered, have achieved at least sufficient functional recovery to “re-engage” in the full range of daily activities. Of course, we continue to search for more effective treatments for them.