Lecture abstract: SARS-CoV-2 is known to disrupt multiple critical endocrinological systems. Sharp increases in endocrine-related abnormalities have been reported, which intensified after the rollout of mRNA vaccines. Excessive catecholamine activity may be the bridge that links mRNA vaccines with the rise in cases of myocarditis and sudden deaths, in particular among young males and male athletes. My lecture will aim to show: the link between spike protein, mRNA, and reported endocrine diseases; when and how to detect endocrine and hormonal abnormalities; expected future effects and disease burden; and effective and potential treatments, as well as active prevention measures.